TEAM MEMBERS
Inès Avenel
Institute: Amsterdam UMC
Supervised by: Dr. Maarten Bijlsma and Dr. Hanneke van Laarhoven
Project contribution: To reveal baseline growth patterns and clonal dynamics under therapeutic pressure.
Morgan McLaughlin
Institute: Amsterdam UMC
Supervised by: Dr. Gustav Strijkers and Dr. Bram Coolen
Project contribution: Development of a comprehensive multi-parametric imaging protocol for response prediction, facilitating a collection of readouts from the same subject in a single imaging session.
Rok Žiberna
Institute: Amsterdam UMC
Supervised by: Dr. Sarah Derks
Project contribution: To identify immunological processes associated with therapy resistance and define and test immunological targets for novel immunomodulatory strategies.
Giulia Costella
Institute: Leipzig University
Supervised by: Prof. Dr. Florian Lordick and Dr. Achim Aigner
Project contribution: Explore and validate candidate targets involved in the acquired resistance of esophagus cancer cells
Natasha Salmelin
Institute: Institute of Cancer Research of Montpellier, l'Institut de Recherche en Cancérologie de Montpellier (IRCM)
Supervised by: Dr Henri-Alexandre Michaud, Dr. Matthieu Lacroix, MD Antoine Adenis and Prof. Dr. Nathalie Bonnefoy
Project contribution: Spatial exploration of the tumor immune microenvironment and expression patterns of metabolic markers in localized esophageal adenocarcinoma.
Angeline Enton Raj
Institute: Karolinska Institutet
Supervised by: Prof. Dr. Magnus Nilsson, Dr. Andrea Ponzetta, Prof. Dr. Fredrik Klevebro
Project contribution: To assess short- and long-term outcomes of operative EAC treatment in terms of survival, resection rate, complication rate, and risk for recurrent disease.
Laurie Clauzon
Institute: University of Palermo
Supervised by: Prof. D. Giorgio Stassi
Project contribution: To identify and validate cancer stem cell biomarkers associated with a hybrid epithelial/mesenchymal (E/M) resistance phenotype.
Zuzanna Trybala
Institute: Masaryk Memorial Cancer Institute (MMCI)
Supervised by: Dr. Radka Obermannová
Project contribution: To reveal the mechanisms that activate kinase signaling in esophageal adenocarcinoma by phosophoproteomics.
Eleonora Moroncini
Institute: Nordic Bioscience
Supervised by: Dr. Nicholas Willumsen
Project contribution: To measure and validate extracellular matrix-related protein fingerprint biomarkers in serum from esophageal adenocarcinoma patients in relation to outcomes.
Radhika Dhekane
Institute: REACT4LIFE SRL
Supervised by: Dr. Silvia Scaglione
Project contribution: To use a novel organ-on-chip model to gain a better understanding of the mesenchymal/epithelial transition, the tumor-stroma interaction, and drug resistance in esophageal adenocarcinoma.
